A Versatile Toolkit to Produce Sensitive FRET Biosensors to Visualize Signaling in Time and Space-Reference-Cited by-同舟云学术

A Versatile Toolkit to Produce Sensitive FRET Biosensors to Visualize Signaling in Time and Space

Published:2013-07-23 Issue:285 Volume:6 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Fritz Rafael D.¹,Letzelter Michel¹,Reimann Andreas¹,Martin Katrin¹,Fusco Ludovico¹,Ritsma Laila²,Ponsioen Bas²,Fluri Erika¹,Schulte-Merker Stefan²³,van Rheenen Jacco²⁴,Pertz Olivier¹

Affiliation:

1. Institute of Biochemistry and Genetics, Department of Biomedicine, University of Basel, Mattenstrasse 28, 4058 Basel, Switzerland.

2. Hubrecht Institute–Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands.

3. Experimental Zoology Group, Wageningen UR, 6708 Wageningen, the Netherlands.

4. Cancer Genomics Netherlands, 3508 TC Utrecht, the Netherlands.

Abstract

Next-generation biosensors enable in vivo monitoring of ERK activity and detection of RhoA activity in small cellular extensions.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference40 articles.

1. The Fluorescent Toolbox for Assessing Protein Location and Function

2. Coordination of Rho GTPase activities during cell protrusion

3. Spatio-temporal Rho GTPase signaling – where are we now?