Structure-function guided modeling of chemokine-GPCR specificity for the chemokine XCL1 and its receptor XCR1-Reference-Cited by-同舟云学术

Structure-function guided modeling of chemokine-GPCR specificity for the chemokine XCL1 and its receptor XCR1

Published:2019-09-03 Issue:597 Volume:12 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Fox Jamie C.¹^ORCID,Thomas Monica A.¹^ORCID,Dishman Acacia F.¹^ORCID,Larsen Olav²^ORCID,Nakayama Takashi³,Yoshie Osamu⁴,Rosenkilde Mette Marie²^ORCID,Volkman Brian F.¹^ORCID

Affiliation:

1. Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

2. Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen DK-2200, Denmark.

3. Divison of Chemotherapy, Kindai University Faculty of Pharmacy, Higashi-osaka 577, Japan.

4. The Health and Kampo Institute, 1-11-10 Murasakiyama, Sendai, Miyagi 982-3205, Japan.

Abstract

Key amino acids in the chemokine XCL1 mediate its specificity for and activation of its receptor XCR1.

Funder

National Institutes of Health

Ministry of Education, Culture, Sports, Science, and Technology

Lundbeckfonden

Novo Nordisk

Carlsberg Foundation

Hørslev Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference86 articles.

1. Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development

2. Crucial roles of XCR1-expressing dendritic cells and the XCR1-XCL1 chemokine axis in intestinal immune homeostasis

3. Laser-Assisted Intradermal Delivery of Adjuvant-Free Vaccines Targeting XCR1+ Dendritic Cells Induces Potent Antitumoral Responses

4. Local and systemic effects of an allogeneic tumor cell vaccine combining transgenic human lymphotactin with interleukin-2 in patients with advanced or refractory neuroblastoma

5. Lymphotactin gene-modified bone marrow dendritic cells act as more potent adjuvants for peptide delivery to induce specific antitumor immunity;Cao X.;J. Immunol.,1998

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Genomic basis of Y‐linked dwarfism in cichlids pursuing alternative reproductive tactics;Molecular Ecology;2023-02-09

2. Physiology of chemokines in the cancer microenvironment;American Journal of Physiology-Cell Physiology;2023-01-01

3. Identification of circRNA expression profiles and the potential role of hsa_circ_0006916 in silicosis and pulmonary fibrosis;Toxicology;2023-01

4. Automated Path Searching Reveals the Mechanism of Hydrolysis Enhancement by T4 Lysozyme Mutants;International Journal of Molecular Sciences;2022-11-23

5. Insights into the dynamic interactions at chemokine-receptor interfaces and mechanistic models of chemokine binding;Journal of Structural Biology;2022-09