1. Centre for Systems Biology, Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada.
2. Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
3. Department of Statistics and Applied Probability, National University of Singapore, Singapore 117546, Singapore.
4. Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117597, Singapore.