Oligomerization of MrgC11 and μ-opioid receptors in sensory neurons enhances morphine analgesia-Reference-Cited by-同舟云学术

Oligomerization of MrgC11 and μ-opioid receptors in sensory neurons enhances morphine analgesia

Published:2018-06-19 Issue:535 Volume:11 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

He Shao-Qiu¹,Xu Qian²³,Tiwari Vinod¹,Yang Fei¹^ORCID,Anderson Michael¹,Chen Zhiyong¹,Grenald Shaness A.¹,Raja Srinivasa N.¹^ORCID,Dong Xinzhong²³,Guan Yun¹^ORCID

Affiliation:

1. Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

2. Solomon H. Snyder Department of Neuroscience, Center for Sensory Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

3. Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Abstract

Activating the peripheral sensory receptor MrgC11 may improve opioid use for pain management.

Funder

National Institutes of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference64 articles.

1. Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis

2. Facilitation of μ-Opioid Receptor Activity by Preventing δ-Opioid Receptor-Mediated Codegradation

3. Building a new conceptual framework for receptor heteromers

4. A role for heterodimerization of and opiate receptors in enhancing morphine analgesia

5. Attacking pain at its source: new perspectives on opioids

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