IRF6 and TAK1 coordinately promote the activation of HIPK2 to stimulate apoptosis during palate fusion-Reference-Cited by-同舟云学术

IRF6 and TAK1 coordinately promote the activation of HIPK2 to stimulate apoptosis during palate fusion

Published:2019-08-06 Issue:593 Volume:12 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Ke Chen-Yeh¹²^ORCID,Mei Hua-Hsuan¹^ORCID,Wong Fen-Hwa²^ORCID,Lo Lun-Jou¹^ORCID

Affiliation:

1. Department of Plastic and Reconstructive Surgery, and Craniofacial Research Center, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan

2. Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University, Taipei, Taiwan

Abstract

The kinase HIPK2 promotes cell death that is necessary for proper palate development in mice.

Funder

Ministry of Education

Chang-Gung Memorial Hospital

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference70 articles.

1. Palate development

2. Cleft palate: players, pathways, and pursuits

3. Epithelial-mesenchymal transformation during palatal fusion: carboxyfluorescein traces cells at light and electron microscopic levels

4. Medial edge epithelium fate traced by cell lineage analysis during epithelial-mesenchymal transformation in vivo

5. Transforming growth factor β (TGFβ) signalling in palatal growth, apoptosis and epithelial mesenchymal transformation (EMT)

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