Arginine Starvation Impairs Mitochondrial Respiratory Function in ASS1-Deficient Breast Cancer Cells-Reference-Cited by-同舟云学术

Arginine Starvation Impairs Mitochondrial Respiratory Function in ASS1-Deficient Breast Cancer Cells

Published:2014-04 Issue:319 Volume:7 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Qiu Fuming¹²,Chen Yun-Ru¹,Liu Xiyong¹,Chu Cheng-Ying³,Shen Li-Jiuan⁴,Xu Jinghong⁵,Gaur Shikha¹,Forman Henry Jay⁶⁷,Zhang Hang⁸,Zheng Shu⁸,Yen Yun¹³⁹,Huang Jian⁸,Kung Hsing-Jien³¹⁰¹¹,Ann David K.¹³⁹

Affiliation:

1. Department of Molecular Pharmacology, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.

2. Department of Medical Oncology, Zhejiang University School of Medicine, Hangzhou 310012, China.

3. Integrated Laboratory, Center of Translational Medicine, Taipei Medical University, Taipei 110, Taiwan.

4. Graduate Institute of Clinical Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan.

5. Department of Pathology, Zhejiang University School of Medicine, Hangzhou 310012, China.

6. Life & Environmental Sciences Unit, University of California, Merced, Merced, CA 95343, USA.

7. Ethel Percy Andrus Gerontology Center, Davis School of Gerontology, University of Southern California, 3715 McClintock Avenue, Los Angeles, CA 90089–0191, USA.

8. Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310012, China.

9. Irell & Manella Graduate School of Biological Sciences, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.

10. Department of Biochemistry and Molecular Medicine, UC Davis Comprehensive Cancer Center, Sacramento, CA 95817, USA.

11. National Health Research Institutes, Zhunan Town, Miaoli County 350, Taiwan.

Abstract

Tumors that cannot make arginine undergo mitochondrial dysfunction in the absence of extracellular arginine and die by autophagy.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference83 articles.

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