Tandem phosphorylation within an intrinsically disordered region regulates ACTN4 function-Reference-Cited by-同舟云学术

Tandem phosphorylation within an intrinsically disordered region regulates ACTN4 function

Author:

Travers Timothy¹,Shao Hanshuang²,Joughin Brian A.³,Lauffenburger Douglas A.⁴,Wells Alan²,Camacho Carlos J.¹

Affiliation:

1. Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA 15260, USA.

2. Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15260, USA.

3. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

4. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Abstract

Phosphorylation of a tyrosine in the disordered N-terminal region of ACTN4 functions as a switch exposing a second site for phosphorylation.

Funder

NIH

Commonwealth of Pennsylvania Department of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference62 articles.

Cited by 24 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献