A predictive model of gene expression reveals the role of network motifs in the mating response of yeast-Reference-Cited by-同舟云学术

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A predictive model of gene expression reveals the role of network motifs in the mating response of yeast

Published:2021-02-16 Issue:670 Volume:14 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Pomeroy Amy E.¹^ORCID,Peña Matthew I.²^ORCID,Houser John R.²,Dixit Gauri³,Dohlman Henrik G.³^ORCID,Elston Timothy C.²⁴^ORCID,Errede Beverly³^ORCID

Affiliation:

1. Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

2. Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

3. Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

4. Computational Medicine Program, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Abstract

Signaling network motifs ensure appropriate transcriptional responses to distinct pheromone dynamics in yeast.

Funder

National Institute of General Medical Sciences

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference81 articles.

1. Network motifs: theory and experimental approaches

2. Oscillatory stimuli differentiate adapting circuit topologies

3. Microfluidic devices for measuring gene network dynamics in single cells

4. Oscillatory stress stimulation uncovers an Achilles heel of the yeast MAPK signaling network

5. Frequency modulation of ERK activation dynamics rewires cell fate

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1. Multiscale Modeling of Bistability in the Yeast Polarity Circuit;Cells;2024-08-15

2. Transient frequency preference responses in cell signaling systems;npj Systems Biology and Applications;2024-08-11

3. Data integration strategies for whole-cell modeling;FEMS Yeast Research;2024

4. Mechanism of Yeast Mating Signal Pathway and Its Synthetic Biology Applications;PROG BIOCHEM BIOPHYS;2023

5. Molecular switch architecture determines response properties of signaling pathways;Proceedings of the National Academy of Sciences;2021-03-09

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