SOX9 is required for kidney fibrosis and activates NAV3 to drive renal myofibroblast function-Reference-Cited by-同舟云学术

SOX9 is required for kidney fibrosis and activates NAV3 to drive renal myofibroblast function

Published:2021-03-02 Issue:672 Volume:14 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Raza Sayyid¹²^ORCID,Jokl Elliot¹²^ORCID,Pritchett James³,Martin Katherine¹²^ORCID,Su Kim¹²^ORCID,Simpson Kara¹²^ORCID,Birchall Lindsay¹²,Mullan Aoibheann F.¹²,Athwal Varinder S.¹²⁴^ORCID,Doherty Daniel T.¹²^ORCID,Zeef Leo⁵^ORCID,Henderson Neil C.⁶^ORCID,Kalra Philip A.⁷^ORCID,Hanley Neil A.¹²⁴,Piper Hanley Karen¹²^ORCID

Affiliation:

1. Wellcome Centre for Cell-Matrix Research, Faculty of Biology, Medicine and Health and Manchester Academic Health Science Centre, University of Manchester, Oxford Road, Manchester M13 9PT, UK.

2. Division of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester, UK.

3. School of Healthcare Science, Manchester Metropolitan University, Manchester M1 5GD, UK.

4. Manchester University NHS Foundation Trust, Oxford Road, Manchester M13 9PT, UK.

5. Bioinformatics Core Facility, Faculty of Life Sciences, University of Manchester, Manchester, UK.

6. MRC Centre for Inflammation Research, Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK.

7. Salford Royal NHS Foundation Trust, Stott Lane, Salford, UK.

Abstract

Loss of the transcription factor SOX9 reduces experimentally induced kidney fibrosis in mice.

Funder

Wellcome

Medical Research Council

National Institute for Health Research

Kidney Research UK

Kidneys for Life

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference55 articles.

1. Cellular and molecular mechanisms in kidney fibrosis

2. Matrix-Producing Cells in Chronic Kidney Disease: Origin, Regulation, and Activation

3. Cellular and molecular mechanisms of renal fibrosis

4. Mechanosensing and fibrosis

5. Tissue mechanics and fibrosis

Cited by 20 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. SOX9-regulated matrix proteins predict poor outcomes in patients with COVID-19 and pulmonary fibrosis;2024-01-23

2. ERK1/2-dependent activity of SOX9 is required for sublytic C5b-9-induced expression of FGF1, PDGFα, and TGF-β1 in rat Thy-1 nephritis;International Immunopharmacology;2024-01

3. Neuron navigators: A novel frontier with physiological and pathological implications;Molecular and Cellular Neuroscience;2023-12

4. PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis;Cell Reports;2023-11

5. The Role of SOX9 in IGF-II-Mediated Pulmonary Fibrosis;International Journal of Molecular Sciences;2023-07-08