ERK phosphorylation is RAF independent in naïve and activated B cells but RAF dependent in plasma cell differentiation-Reference-Cited by-同舟云学术

ERK phosphorylation is RAF independent in naïve and activated B cells but RAF dependent in plasma cell differentiation

Published:2021-05-11 Issue:682 Volume:14 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Scheffler Laura¹^ORCID,Feicht Samantha¹²^ORCID,Babushku Tea¹^ORCID,Kuhn Laura B.¹,Ehrenberg Stefanie¹,Frankenberger Samantha¹,Lehmann Frank M.²^ORCID,Hobeika Elias³⁴^ORCID,Jungnickel Berit²⁵,Baccarini Manuela⁶^ORCID,Bornkamm Georg W.²,Strobl Lothar J.¹^ORCID,Zimber-Strobl Ursula¹^ORCID

Affiliation:

1. Research Unit of Gene Vectors, Helmholtz Center Munich, German Research Center for Environmental Health GmbH, Marchioninistrasse 25, D-81377 Munich, Germany.

2. Institute for Clinical Molecular Biology and Tumor Genetics, Helmholtz Center Munich, German Research Center for Environmental Health GmbH, Marchioninistrasse 25, D-81377 Munich, Germany.

3. Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, Stübeweg 51, D-79108 Freiburg, Germany.

4. Institute of Immunology, Ulm University Medical Center, Albert-Einstein-Allee 11, D-89070 Ulm, Germany.

5. Department of Cell Biology, Institute of Biochemistry and Biophysics, Center for Molecular Biomedicine, Friedrich-Schiller University Jena, Hans-Knoell-Strasse 2, D-07745 Jena, Germany.

6. Department of Microbiology, Immunobiology, and Genetics, Center for Molecular Biology of the University of Vienna, Max Perutz Labs, Dr. Bohr-Gasse 9, 1030 Vienna, Austria.

Abstract

The activation of ERK in mouse B cells requires RAFs during only some stages of differentiation.

Funder

Wilhelm Sander-Stiftung

Deutsche Forschungsgemeinschaft

Sander Stiftung

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference51 articles.

1. Raf Family Kinases: Old Dogs Have Learned New Tricks