Apoptotic Cells Activate the “Phoenix Rising” Pathway to Promote Wound Healing and Tissue Regeneration

Author:

Li Fang1,Huang Qian123,Chen Jiang45,Peng Yuanlin6,Roop Dennis R.45,Bedford Joel S.6,Li Chuan-Yuan157

Affiliation:

1. Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO 80045, USA.

2. Center for Laboratory Research, First People’s Hospital, Shanghai Jiaotong University, Shanghai 200080, China.

3. National Laboratory for Oncogene and Related Genes Research, Cancer Institute of Shanghai Jiaotong University, Shanghai 200032, China.

4. Department of Dermatology, University of Colorado School of Medicine, Aurora, CO 80045, USA.

5. Charles C. Gates Regenerative Medicine and Stem Cell Biology Program, University of Colorado School of Medicine, Aurora, CO 80045, USA.

6. Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA.

7. Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA.

Abstract

Caspases in dying cells trigger the release of growth signals that promote tissue repair.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

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