The Tetraspanin CD37 Orchestrates the α 4 β 1 Integrin–Akt Signaling Axis and Supports Long-Lived Plasma Cell Survival-Reference-Cited by-同舟云学术

The Tetraspanin CD37 Orchestrates the α 4 β 1 Integrin–Akt Signaling Axis and Supports Long-Lived Plasma Cell Survival

Published:2012-11-13 Issue:250 Volume:5 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

van Spriel Annemiek B.¹,de Keijzer Sandra¹,van der Schaaf Alie¹,Gartlan Kate H.²,Sofi Mariam²,Light Amanda³,Linssen Peter C.⁴,Boezeman Jan B.⁴,Zuidscherwoude Malou¹,Reinieren-Beeren Inge¹,Cambi Alessandra¹,Mackay Fabienne²,Tarlinton David M.³,Figdor Carl G.¹,Wright Mark D.²

Affiliation:

1. Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen 6525 GA, Netherlands.

2. Department of Immunology, Monash University, Alfred Medical Research and Education Precinct, Melbourne, VIC 3005, Australia.

3. Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3050, Australia.

4. Laboratory of Hematology, Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen 6500 HB, Netherlands.

Abstract

Antibody-producing B cells require CD37-dependent integrin signaling for long-term survival.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference55 articles.

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3. Akt1 and Akt2 promote peripheral B-cell maturation and survival

4. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations.

5. The primary germinal center response in mice

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