A systems-wide screen identifies substrates of the SCF βTrCP ubiquitin ligase-Reference-Cited by-同舟云学术

A systems-wide screen identifies substrates of the SCF βTrCP ubiquitin ligase

Published:2014-12-16 Issue:356 Volume:7 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Low Teck Yew¹²,Peng Mao¹²,Magliozzi Roberto³,Mohammed Shabaz¹²,Guardavaccaro Daniele³,R. Heck Albert J.¹²

Affiliation:

1. Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, Netherlands.

2. Netherlands Proteomics Center, Padualaan 8, 3584 CH Utrecht, Netherlands.

3. Hubrecht Institute–KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, Netherlands.

Abstract

A proteomic and bioinformatic approach provides a method for identifying substrates and regulators of ubiquitin E3 ligases.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference98 articles.

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2. The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction

3. Ubiquitin: structures, functions, mechanisms

4. The Comparative Proteomics of Ubiquitination in Mouse

5. The Fbw7 and BetaTRCP E3 ubiquitin ligases and their roles in tumorigenesis

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