B cell antigen receptors of the IgM and IgD classes are clustered in different protein islands that are altered during B cell activation

Author:

Maity Palash Chandra12,Blount Amy3,Jumaa Hassan24,Ronneberger Olaf15,Lillemeier Björn F.3,Reth Michael12

Affiliation:

1. BIOSS Centre for Biological Signalling Studies, University of Freiburg, D-79104 Freiburg, Germany.

2. Department of Molecular Immunology, Institute of Biology III at the Faculty of Biology of the University of Freiburg, D-79104, and at the Max Planck Institute of Immunobiology and Epigenetics, D-79108 Freiburg, Germany.

3. Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

4. Institute of Immunology, Ulm University, D-89081 Ulm, Germany.

5. Institute of Computer Science, University of Freiburg, D-79110 Freiburg Germany.

Abstract

Antigen stimulates the dispersion and remodeling of preformed distinct clusters of B cell receptors on the cell surface.

Funder

Excellence Initiative of the German Federal and State Governments

ERC

Deutsche Forschungsgemeinschaft

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

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