Regulation of brain glutamate metabolism by nitric oxide and S-nitrosylation-Reference-Cited by-同舟云学术

Regulation of brain glutamate metabolism by nitric oxide and S-nitrosylation

Published:2015-07-07 Issue:384 Volume:8 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Raju Karthik¹,Doulias Paschalis-Thomas²,Evans Perry³,Krizman Elizabeth N.⁴,Jackson Joshua G.⁴,Horyn Oksana⁵,Daikhin Yevgeny⁵,Nissim Ilana⁵,Yudkoff Marc⁵,Nissim Itzhak⁵⁶,Sharp Kim A.⁶,Robinson Michael B.¹⁴⁷,Ischiropoulos Harry¹²⁷

Affiliation:

1. Neuroscience Graduate Group, University of Pennsylvania, Philadelphia, PA 19104, USA.

2. Division of Neonatology, Department of Pediatrics, Children’s Hospital of Philadelphia Research Institute, Philadelphia, PA 19104, USA.

3. Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia Research Institute, Philadelphia, PA 19104, USA.

4. Division of Neurology, Department of Pediatrics, Children’s Hospital of Philadelphia Research Institute, Philadelphia, PA 19104, USA.

5. Division of Genetic and Metabolic Disease, Department of Pediatrics, Children’s Hospital of Philadelphia Research Institute, Philadelphia, PA 19104, USA.

6. Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104, USA.

7. Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.

Abstract

Protein S-nitrosylation controls the brain’s use of glutamate for energy or neurotransmission.

Funder

National Institute on Aging (NIA)

National Heart, Lung, and Blood Institute (NHLBI)

National Institute of Environmental Health Sciences (NIEHS) Center of Excellence in Environmental Toxicology

NIA

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

National Institute of Child Health and Human Development (NICHD)

Intellectual and Developmental Disabilities Research Center (IDDRC)