DDAH2 suppresses RLR-MAVS–mediated innate antiviral immunity by stimulating nitric oxide–activated, Drp1-induced mitochondrial fission-Reference-Cited by-同舟云学术

DDAH2 suppresses RLR-MAVS–mediated innate antiviral immunity by stimulating nitric oxide–activated, Drp1-induced mitochondrial fission

Published:2021-04-13 Issue:678 Volume:14 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Huang Shan¹²^ORCID,Li Zexing²,Wu Zewen¹³^ORCID,Liu Chang¹²^ORCID,Yu Minghang¹,Wen Mingjie¹^ORCID,Zhang Liyun³^ORCID,Wang Xi¹²³^ORCID

Affiliation:

1. Department of Immunology, School of Basic Medical Sciences; Advanced Innovation Center for Human Brain Protection, Beijing Key Laboratory for Cancer Invasion and Metastasis, Department of Oncology, Capital Medical University, Beijing 100069, China.

2. Department of Cell Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070, China.

3. Department of Rheumatology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Shanxi Bethune Hospital Affiliated to Shanxi Medical University, Taiyuan 30032, Shanxi, China.

Abstract

DDAH2 inhibits antiviral signaling by promoting mitochondrial fission.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Tianjin City

Ministry of Science and Technology, Government of the People’s Republic of Bangladesh

Five year Plan

Foundation for Innovative Research Groups of the National Natural Science Foundation of China

Support Project of High-level Teachers in Beijing Municipal Universities

the Ministry of Science and Technology of People’s Republic of China

Publisher

American Association for the Advancement of Science (AAAS)