Regulation of thymocyte trafficking by Tagap, a GAP domain protein linked to human autoimmunity-Reference-Cited by-同舟云学术

Regulation of thymocyte trafficking by Tagap, a GAP domain protein linked to human autoimmunity

Published:2018-06-12 Issue:534 Volume:11 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Duke-Cohan Jonathan S.¹²^ORCID,Ishikawa Yuki²³^ORCID,Yoshizawa Akihiro¹²^ORCID,Choi Young-Il¹²^ORCID,Lee Chin-Nien²³^ORCID,Acuto Oreste⁴,Kissler Stephan²³^ORCID,Reinherz Ellis L.¹²^ORCID

Affiliation:

1. Laboratory of Immunobiology, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.

2. Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.

3. Immunobiology Section, Joslin Diabetes Center, Boston, MA 02215, USA.

4. Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK.

Abstract

The GTPase-activating protein Tagap enables thymocytes to properly migrate within the thymus to undergo selection.

Funder

NIH Office of the Director

Wellcome Trust

Joslin Diabetes Center

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference57 articles.

1. T-cell selection in the thymus: a spatial and temporal perspective

2. Dynamic control of β1 integrin adhesion by the plexinD1-sema3E axis

3. Dynamic membrane-cytoskeletal interactions: specific association of integrin and talin arises in vivo after phorbol ester treatment of peripheral blood lymphocytes.

4. Kindlins: essential regulators of integrin signalling and cell–matrix adhesion

5. PlexinD1 Glycoprotein Controls Migration of Positively Selected Thymocytes into the Medulla

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