Mechanism of Stretch-Induced Activation of the Mechanotransducer Zyxin in Vascular Cells-Reference-Cited by-同舟云学术

Mechanism of Stretch-Induced Activation of the Mechanotransducer Zyxin in Vascular Cells

Published:2012-12-11 Issue:254 Volume:5 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Suresh Babu Sahana¹,Wojtowicz Agnieszka¹,Freichel Marc²,Birnbaumer Lutz³,Hecker Markus¹,Cattaruzza Marco¹

Affiliation:

1. Institute of Physiology and Pathophysiology, Division of Cardiovascular Physiology, University of Heidelberg, D-69120 Heidelberg, Germany.

2. Institute of Pharmacology, University of Heidelberg, D-69120 Heidelberg, Germany.

3. Laboratory of Neurobiology, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA.

Abstract

Multiple steps drive the stretch-induced nuclear translocation of the mechanotransducer zyxin.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference45 articles.

1. Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology

2. Cardiac Hypertrophy: The Good, the Bad, and the Ugly

3. Molecular Characterization of Human Zyxin

4. Targeted Disruption of the Murine zyxin Gene

5. Focal Adhesion Protein Zyxin Is a Mechanosensitive Modulator of Gene Expression in Vascular Smooth Muscle Cells

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