SMAC mimetics and RIPK inhibitors as therapeutics for chronic inflammatory diseases

Author:

Jensen Simone1ORCID,Seidelin Jakob Benedict1ORCID,LaCasse Eric Charles2ORCID,Nielsen Ole Haagen1ORCID

Affiliation:

1. Department of Gastroenterology, Medical Section, Herlev Hospital, University of Copenhagen, 1 Borgmester Ib Juuls Vej, DK-2730 Herlev, Denmark.

2. Apoptosis Research Centre, Children’s Hospital of Eastern Ontario Research Institute, 401 Smyth Road, Ottawa, Ontario K1H 8L1, Canada.

Abstract

Although mainly investigated as anticancer therapies, SMAC mimetics and RIPK inhibitors may fight chronic inflammation.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

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