Lung Myeloid Dendritic Cells Coordinately Induce T H 1 and T H 17 Responses in Human Emphysema-Reference-Cited by-同舟云学术

Lung Myeloid Dendritic Cells Coordinately Induce T H 1 and T H 17 Responses in Human Emphysema

Published:2009-10-28 Issue:4 Volume:1 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Shan Ming¹²,Cheng Han-Fang¹²,Song Li-zhen¹,Roberts Luz¹,Green Linda³,Hacken-Bitar Joan⁴,Huh Joseph⁵⁶,Bakaeen Faisal⁵⁶,Coxson Harvey O.⁷,Storness-Bliss Claudine⁷,Ramchandani Mahesh⁸,Lee Seung-Hyo⁹,Corry David B.¹²,Kheradmand Farrah¹²

Affiliation:

1. Department of Medicine, Section of Pulmonary and Critical Care, Baylor College of Medicine, Houston, TX 77030, USA.

2. Department of Immunology, Baylor College of Medicine, Houston, TX 77030, USA.

3. Department of Pathology, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX 77030, USA.

4. Department of Radiology, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX 77030, USA.

5. Department of Surgery, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX 77030, USA.

6. Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.

7. Department of Radiology, Vancouver General Hospital, Vancouver, British Columbia, Canada V6Z 1Y6.

8. The Methodist Hospital, Houston, TX 77030, USA.

9. Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon 305-701, South Korea.

Abstract

Specialized immune cells in the lungs of patients with emphysema create an inflammatory environment that drives lung destruction in a characteristic autoimmune reaction.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference63 articles.

1. How cigarette smoke skews immune responses to promote infection, lung disease and cancer

2. Immunology of asthma and chronic obstructive pulmonary disease

3. Animal Models for COPD

4. Predictors of Mortality in Chronic Obstructive Pulmonary Disease

5. National Emphysema Treatment Trial State of the Art: Genetics of Emphysema

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