Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation-Reference-Cited by-同舟云学术

Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation

Published:2015-04-03 Issue:3 Volume:1 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Tang Jun¹²^ORCID,Lobatto Mark E.¹³,Hassing Laurien¹³,van der Staay Susanne¹³,van Rijs Sarian M.¹³,Calcagno Claudia¹,Braza Mounia S.¹,Baxter Samantha¹,Fay Francois¹,Sanchez-Gaytan Brenda L.¹,Duivenvoorden Raphaël³,Sager Hendrik B.⁴,Astudillo Yaritzy M.⁵,Leong Wei¹²,Ramachandran Sarayu¹,Storm Gert⁶⁷,Pérez-Medina Carlos¹,Reiner Thomas⁸,Cormode David P.⁹,Strijkers Gustav J.¹⁰,Stroes Erik S. G.³,Swirski Filip K.⁴,Nahrendorf Matthias⁴,Fisher Edward A.⁵,Fayad Zahi A.¹,Mulder Willem J. M.¹³

Affiliation:

1. Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

2. Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

3. Department of Vascular Medicine, Academic Medical Center, 1105 AZ Amsterdam, Netherlands.

4. Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

5. Department of Medicine (Cardiology) and Cell Biology, Marc and Ruti Bell Program in Vascular Biology, NYU School of Medicine, New York, NY 10016, USA.

6. Department of Pharmaceutics, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, 3584 CG Utrecht, Netherlands.

7. Department of Controlled Drug Delivery, MIRA Institute for Biomedical Engineering and Technical Medicine, University of Twente, 7500 AE Enschede, Netherlands.

8. Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

9. Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.

10. Department of Biomedical Engineering and Physics, Academic Medical Center, 1105 AZ Amsterdam, Netherlands.

Abstract

Nanoparticle-based delivery of simvastatin inhibits plaque macrophage proliferation in apolipoprotein E–deficient mice.

Funder

National Institutes of Health

National Heart, Lung, and Blood Institute

Harold S. Geneen Charitable Trust Award

The Netherlands Organisation for Scientific Research

American Heart Association Founders Affiliate Predoctoral Award

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