PAI-1 is a critical regulator of FGF23 homeostasis-Reference-Cited by-同舟云学术

PAI-1 is a critical regulator of FGF23 homeostasis

Author:

Eren Mesut¹²^ORCID,Place Aaron T.¹²^ORCID,Thomas Paul M.³^ORCID,Flevaris Panagiotis¹²,Miyata Toshio⁴,Vaughan Douglas E.¹²^ORCID

Affiliation:

1. Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

2. Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

3. Proteomics Center of Excellence, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

4. United Centers for Advanced Research and Translational Medicine, Tohoku University Graduate School of Medicine, Miyagi, Japan.

Abstract

Pharmacological inhibition of PAI-1 augments proteolytic clearance of FGF23.

Funder

National Institutes of Health

National Heart, Lung, and Blood Institute

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference49 articles.

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