Stratified ubiquitination of RIG-I creates robust immune response and induces selective gene expression-Reference-Cited by-同舟云学术

Stratified ubiquitination of RIG-I creates robust immune response and induces selective gene expression

Published:2017-09 Issue:9 Volume:3 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Xian Huifang¹²^ORCID,Xie Weihong¹²^ORCID,Yang Shuai¹²^ORCID,Liu Qingxiang¹²^ORCID,Xia Xiaojun²,Jin Shouheng¹²,Sun Tingzhe³^ORCID,Cui Jun¹²^ORCID

Affiliation:

1. Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510006, China.

2. State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.

3. School of Life Sciences, Anqing Normal University, Anqing 246011, China.

Abstract

Stratified multisite ubiquitination of RIG-I provides a robust and optimal control of innate antiviral responses.

Funder

National Natural Science Foundation of China

National Key Basic Research Program

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference48 articles.

1. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses