A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy-Reference-Cited by-同舟云学术

A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy

Author:

Yang Mei¹^ORCID,Liang Chen¹,Swaminathan Kunchithapadam²^ORCID,Herrlinger Stephanie¹^ORCID,Lai Fan³^ORCID,Shiekhattar Ramin³,Chen Jian-Fu¹

Affiliation:

1. Department of Genetics and Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.

2. Department of Biological Sciences, National University of Singapore, 117543 Singapore.

3. Department of Human Genetics, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

Abstract

A dual role of the C9ORF72/SMCR8-containing complex in autophagy initiation and autophagic flux.

Funder

National Institutes of Health

National Institute of General Medical Sciences

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference63 articles.

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