Age-associated molecular changes are deleterious and may modulate life span through diet

Author:

Lee Sang-Goo12,Kaya Alaattin1,Avanesov Andrei S.1ORCID,Podolskiy Dmitriy I.1ORCID,Song Eun Ju34,Go Du-Min5,Jin Gwi-Deuk6,Hwang Jae Yeon6,Kim Eun Bae67,Kim Dae-Yong5,Gladyshev Vadim N.1

Affiliation:

1. Division of Genetics, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.

2. Department of Bioinspired Science, Ewha Womans University, Seoul 03760, South Korea.

3. Ewha Laboratory Animal Genomic Center, Institute of Molecular Life Sciences and Technology, Office of Research Affairs, Ewha Womans University, Seoul 03760, South Korea.

4. Department of Veterinary Physiology, College of Veterinary Medicine, BK21 PLUS Creative Veterinary Research Center, Seoul National University, Seoul 08826, South Korea.

5. Laboratory of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Seoul 08826, South Korea.

6. Department of Animal Life Science, Kangwon National University, Chuncheon 24341, South Korea.

7. Division of Applied Animal Science, Kangwon National University, Chuncheon 24341, South Korea.

Abstract

Age-associated molecular changes are deleterious and causally linked with aging and may affect life span through diet.

Funder

National Institute on Aging

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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