Genome-wide signatures of complex introgression and adaptive evolution in the big cats

Author:

Figueiró Henrique V.1,Li Gang2,Trindade Fernanda J.1,Assis Juliana3ORCID,Pais Fabiano3,Fernandes Gabriel3,Santos Sarah H. D.1,Hughes Graham M.4,Komissarov Aleksey5,Antunes Agostinho6,Trinca Cristine S.1,Rodrigues Maíra R.1,Linderoth Tyler7,Bi Ke8,Silveira Leandro9ORCID,Azevedo Fernando C. C.1011,Kantek Daniel112ORCID,Ramalho Emiliano1113ORCID,Brassaloti Ricardo A.14ORCID,Villela Priscilla M. S.14,Nunes Adauto L. V.15,Teixeira Rodrigo H. F.1516,Morato Ronaldo G.1112,Loska Damian1718,Saragüeta Patricia19,Gabaldón Toni171820,Teeling Emma C.4,O’Brien Stephen J.5,Nielsen Rasmus7ORCID,Coutinho Luiz L.14,Oliveira Guilherme321ORCID,Murphy William J.2,Eizirik Eduardo111

Affiliation:

1. Laboratório de Biologia Genômica e Molecular, Faculdade de Biociências, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, Brazil.

2. Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX 77843, USA.

3. Centro de Pesquisa René Rachou, FIOCRUZ/Minas, Belo Horizonte, Minas Gerais, Brazil.

4. School of Biology and Environmental Science, University College Dublin, Dublin, Ireland.

5. Theodosius Dobzhansky Center for Genome Bioinformatics, Saint Petersburg State University, St. Petersburg, Russia.

6. Departamento de Biologia, Faculdade de Ciências and CIIMAR/CIMAR, Universidade do Porto, Porto, Portugal.

7. Department of Integrative Biology, University of California, Berkeley, Berkeley, CA 94720–3140, USA.

8. Computational Genomics Resource Laboratory, California Institute for Quantitative Biosciences and Museum of Vertebrate Zoology, University of California, Berkeley, Berkeley, CA 94720, USA.

9. Instituto Onça-Pintada, Mineiros, Goiás, Brazil.

10. Universidade Federal de São João Del Rey, São João Del Rey, Minas Gerais, Brazil.

11. Instituto Pró-Carnívoros, Atibaia, São Paulo, Brazil.

12. Instituto Chico Mendes de Conservação da Biodiversidade, Brasília, Distrito Federal, Brazil.

13. Instituto de Desenvolvimento Sustentável Mamirauá, Tefé, Amazonas, Brazil.

14. Escola Superior de Agricultura Luiz de Queiroz (ESALQ-USP), Piracicaba, São Paulo, Brazil.

15. Zoológico Municipal de Sorocaba, Sorocaba, São Paulo, Brazil.

16. Programa de Pós-Graduação em Animais Selvagens, Universidade Estadual Paulista–Botucatu, São Paulo, Brazil.

17. Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain.

18. Universitat Pompeu Fabra, Barcelona, Spain.

19. Instituto de Biología y Medicina Experimental, Buenos Aires, Argentina.

20. Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.

21. Instituto Tecnológico Vale, Belém, Pará, Brazil.

Abstract

Big cat genomes reveal a history of interspecies admixture and adaptive evolution of genes underlying development and sensory perception.

Funder

Russian Science Foundation

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul

Morris Animal Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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