Unveiling massive numbers of cancer-related urinary-microRNA candidates via nanowires

Author:

Yasui Takao123ORCID,Yanagida Takeshi45ORCID,Ito Satoru1ORCID,Konakade Yuki1ORCID,Takeshita Daiki1ORCID,Naganawa Tsuyoshi1ORCID,Nagashima Kazuki4ORCID,Shimada Taisuke1ORCID,Kaji Noritada123ORCID,Nakamura Yuta1ORCID,Thiodorus Ivan Adiyasa1ORCID,He Yong4ORCID,Rahong Sakon26ORCID,Kanai Masaki4ORCID,Yukawa Hiroshi12,Ochiya Takahiro7ORCID,Kawai Tomoji5ORCID,Baba Yoshinobu1289ORCID

Affiliation:

1. Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.

2. ImPACT Research Center for Advanced Nanobiodevices, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.

3. Japan Science and Technology Agency, PRESTO, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan.

4. Institute of Materials Chemistry and Engineering, Kyushu University, 6-1 Kasuga-koen, Kasuga, Fukuoka 816-8580, Japan.

5. Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka-cho, Ibaraki, Osaka 567-0047, Japan.

6. College of Nanotechnology, King Mongkut’s Institute of Technology Ladkrabang, Chalongkrung Road, Ladkrabang, Bangkok 10520, Thailand.

7. Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

8. Health Research Institute, National Institute of Advanced Industrial Science and Technology, Takamatsu 761-0395, Japan.

9. College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan, Republic of China.

Abstract

We demonstrate the first reported methodology using nanowires that unveils massive numbers of cancer-related urinary microRNAs.

Funder

Japan Society for the Promotion of Science

Japan Science and Technology Agency

Japan Agency for Medical Research and Development and New Energy and Industrial Technology Development Organization

Council for Science, Technology and Innovation

Nanotechnology Platform Program (Molecule and Material Synthesis) of the Ministry of Education, Culture, Sports, Science and Technology

Network Joint Research Center for Materials and Devices

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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