Resident memory CD8 + T cells in the upper respiratory tract prevent pulmonary influenza virus infection-Reference-Cited by-同舟云学术

Resident memory CD8 + T cells in the upper respiratory tract prevent pulmonary influenza virus infection

Published:2017-06-09 Issue:12 Volume:2 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Pizzolla Angela¹^ORCID,Nguyen Thi H. O.¹,Smith Jeffrey M.¹^ORCID,Brooks Andrew G.¹^ORCID,Kedzierska Katherine¹,Heath William R.¹²^ORCID,Reading Patrick C.¹³,Wakim Linda M.¹^ORCID

Affiliation:

1. Department of Microbiology and Immunology, University of Melbourne, at Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.

2. The Australian Research Council Centre of Excellence in Advanced Molecular Imaging, The University of Melbourne, Melbourne 3000, Australia.

3. World Health Organization Collaborating Centre for Reference and Research on Influenza, Victorian Infectious Diseases Reference Laboratory, at Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.

Abstract

Nasal tissue–resident memory T cells block influenza virus transmission to the lung, preventing severe pulmonary disease.

Funder

National Health and Medical Research Council

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference43 articles.

1. Severity of Pneumonia Due to New H1N1 Influenza Virus in Ferrets Is Intermediate between That Due to Seasonal H1N1 Virus and Highly Pathogenic Avian Influenza H5N1 Virus

2. Clinical review: Primary influenza viral pneumonia

3. Lung-resident memory CD8 T cells (TRM) are indispensable for optimal cross-protection against pulmonary virus infection