Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins-Reference-Cited by-同舟云学术

Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins

Published:2014-05-30 Issue:6187 Volume:344 Page:1023-1028
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Wilhelm Benjamin G.¹²,Mandad Sunit³,Truckenbrodt Sven¹⁴,Kröhnert Katharina¹,Schäfer Christina¹,Rammner Burkhard¹,Koo Seong Joo⁵,Claßen Gala A.⁵,Krauss Michael⁵,Haucke Volker⁵,Urlaub Henning³⁶,Rizzoli Silvio O.¹

Affiliation:

1. Department of Neuro- and Sensory Physiology, University of Göttingen Medical Center, European Neuroscience Institute, Cluster of Excellence Nanoscale Microscopy and Molecular Physiology of the Brain, Göttingen, Germany.

2. International Max Planck Research School Neurosciences, 37077 Göttingen, Germany.

3. Bioanalytical Mass Spectrometry Group, Max-Planck-Institute for Biophysical Chemistry, 37077 Göttingen, Germany.

4. International Max Planck Research School Molecular Biology, 37077 Göttingen, Germany.

5. Leibniz Institut für Molekulare Pharmakologie, Department of Molecular Pharmacology and Cell Biology, Robert-Rössle-Strasse 10, 13125 Berlin, Germany.

6. Bioanalytics, Department of Clinical Chemistry, University Medical Center Göttingen, 37075 Göttingen, Germany.

Abstract

High-definition view of the synapse Individual neurons communicate with one another via their synapses, so to understand the nervous system, we need to understand in detail how the synapses are organized. Wilhelm et al. present a quantitative molecular-scale image of the “average” synapse populated with realistic renditions of each of the protein components that contribute to the inner workings of neurons. Science , this issue p. 1023

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference46 articles.

1. Protein scaffolds in the coupling of synaptic exocytosis and endocytosis

2. Molecular machines governing exocytosis of synaptic vesicles

3. THE SYNAPTIC VESICLE CYCLE

4. Endosomal sorting of readily releasable synaptic vesicles

5. Loss of Skywalker Reveals Synaptic Endosomes as Sorting Stations for Synaptic Vesicle Proteins

Cited by 611 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Defining a Lewy Body: Running Up the Hill of Shifting Definitions and Evolving Concepts;Journal of Parkinson's Disease;2024-01-23

2. All SNAP25 molecules in the vesicle–plasma membrane contact zone change conformation during vesicle priming;Proceedings of the National Academy of Sciences;2024-01-03

3. Membrane transformations of fusion and budding;Nature Communications;2024-01-02

4. Multiple Sgip1 splice variants inhibit cannabinoid receptor 1 internalization;Gene;2024-01

5. Vesicle condensation induced by synapsin: condensate size, geometry, and vesicle shape deformations;The European Physical Journal E;2024-01