A Brief History of Drosophila 's Contributions to Genome Research-Reference-Cited by-同舟云学术

A Brief History of Drosophila 's Contributions to Genome Research

Published:2000-03-24 Issue:5461 Volume:287 Page:2216-2218
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Rubin Gerald M.¹,Lewis Edward B.²

Affiliation:

1. Howard Hughes Medical Institute and Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720–3200, USA.

2. Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA.

Abstract

The sequence of the Drosophila melanogaster genome presented in this issue of Science is the latest milestone in nine decades of research on this organism. Genetic and physical mapping, whole-genome mutational screens, and functional alteration of the genome by gene transfer were pioneered in metazoans with the use of this small fruit fly. Here we look at some of the instances in which work on Drosophila has led to major conceptual or technical breakthroughs in our understanding of animal genomes.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference51 articles.

1. Sturtevant A. H., Am. Sci. 53, 303 (1965);

2. ; A. H. Sturtevant A History of Genetics (Harper and Row New York 1965) pp. 1–167; H. L. K. Whitehouse Towards an Understanding of the Mechanism of Heredity (Arnold London ed. 2 1969) pp. 1–447.

3. Sturtevant A. H., J. Exp. Zool. 14, 43 (1913).

4. Direct Proof Through Non-Disjunction That the Sex-Linked Genes of Drosophila Are Borne by the X-Chromosome

5. ; Genetics 1 1 (1916).

Cited by 179 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Transcriptomic and metabolomic analyses reveal that lemon extract prolongs Drosophila lifespan by affecting metabolism;Genomics;2024-01

2. Function and regulation of nitric oxide signaling in Drosophila;Molecules and Cells;2024-01

3. Application of nanopesticides and its toxicity evaluation through Drosophila model;Bioprocess and Biosystems Engineering;2023-11-22

4. Targeting Nrf2 signaling pathway and oxidative stress by resveratrol for Parkinson’s disease: an overview and update on new developments;Molecular Biology Reports;2023-05-08

5. Locomotion and brain gene expression exhibit sex-specific non-monotonic dose-response to HFPO-DA during Drosophila melanogaster lifespan;NeuroToxicology;2023-05