Integrated view of Vibrio cholerae in the Americas-Reference-Cited by-同舟云学术

Integrated view of Vibrio cholerae in the Americas

Published:2017-11-10 Issue:6364 Volume:358 Page:789-793
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Domman Daryl¹^ORCID,Quilici Marie-Laure²,Dorman Matthew J.¹^ORCID,Njamkepo Elisabeth²^ORCID,Mutreja Ankur¹³,Mather Alison E.¹⁴,Delgado Gabriella⁵^ORCID,Morales-Espinosa Rosario⁵^ORCID,Grimont Patrick A. D.⁶^ORCID,Lizárraga-Partida Marcial Leonardo⁷^ORCID,Bouchier Christiane⁸^ORCID,Aanensen David M.⁹,Kuri-Morales Pablo¹⁰^ORCID,Tarr Cheryl L.¹¹^ORCID,Dougan Gordon¹³^ORCID,Parkhill Julian¹^ORCID,Campos Josefina¹²^ORCID,Cravioto Alejandro¹³^ORCID,Weill François-Xavier¹²^ORCID,Thomson Nicholas R.¹¹⁴^ORCID

Affiliation:

1. Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton CB10 1SA, UK.

2. Institut Pasteur, Unité des Bactéries Pathogènes Entériques, Paris, 75015, France.

3. Department of Medicine, University of Cambridge, Addenbrooke’s Hospital, Cambridge CB2 0SP, UK.

4. Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, CB3 0ES, UK.

5. Department of Microbiology and Parasitology, Faculty of Medicine, Universidad Nacional Autónoma de México, Mexico, D.F., Mexico.

6. Institut Pasteur, Unité Biodiversité des Bactéries Pathogènes Emergentes, Paris, 75015, France.

7. Centro de Investigación Científica y de Educación Superior de Ensenada, Baja California, (CICESE), Ensenada, Baja California, Mexico.

8. Institut Pasteur, Plate-forme Génomique (PF1), Paris, 75015, France.

9. Centre for Genomic Pathogen Surveillance, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

10. Subsecretaría de Prevención y Promoción de la Salud, Secretaría de Salud, Ciudad de México, Mexico.

11. Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA.

12. Instituto Nacional de Enfermedades Infecciosas, ANLIS, Buenos Aires, Argentina.

13. Faculty of Medicine, Universidad Nacional Autónoma de México, Mexico, D.F., Mexico.

14. London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.

Abstract

Wave upon wave of disease The cholera pathogen, Vibrio cholerae , is considered to be ubiquitous in water systems, making the design of eradication measures apparently fruitless. Nevertheless, local and global Vibrio populations remain distinct. Now, Weill et al. and Domman et al. show that a surprising diversity between continents has been established. Latin America and Africa bear different variants of cholera toxin with different transmission dynamics and ecological niches. The data are not consistent with the establishment of long-term reservoirs of pandemic cholera or with a relationship to climate events. Science , this issue p. 785 , p. 789

Funder

Wellcome Trust

Biotechnology and Biological Sciences Research Council

Investissement d’Avenir

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference85 articles.

1. World Health Organization Cholera ; www.who.int/mediacentre/factsheets/fs107/en/.

2. Vibrio ecology, pathogenesis, and evolution

3. Global Climate and Infectious Disease: The Cholera Paradigm