Natural Variation in a Drosophila Clock Gene and Temperature Compensation-Reference-Cited by-同舟云学术

Natural Variation in a Drosophila Clock Gene and Temperature Compensation

Published:1997-12-19 Issue:5346 Volume:278 Page:2117-2120
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Sawyer Lesley A.¹²,Hennessy J. Michael¹²,Peixoto Alexandre A.¹²,Rosato Ezio¹²,Parkinson Helen¹²,Costa Rodolfo¹²,Kyriacou Charalambos P.¹²

Affiliation:

1. L. A. Sawyer, J. M. Hennessy, A. A. Peixoto, E. Rosato, H. Parkinson, C. P. Kyriacou, Department of Genetics, University of Leicester, LE1 7RH, UK.

2. R. Costa, Dipartimento di Biologia, Universitá di Padova, Via Trieste 75, 35121 Padova, Italy.

Abstract

The threonine-glycine (Thr-Gly) encoding repeat within the clock gene period of Drosophila melanogaster is polymorphic in length. The two major variants (Thr-Gly)17 and (Thr-Gly)20 are distributed as a highly significant latitudinal cline in Europe and North Africa. Thr-Gly length variation from both wild-caught and transgenic individuals is related to the flies' ability to maintain a circadian period at different temperatures. This phenomenon provides a selective explanation for the geographical distribution of Thr-Gly lengths and gives a rare glimpse of the interplay between molecular polymorphism, behavior, population biology, and natural selection.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference33 articles.

1. E. Rosato A. Piccin C. P. Kyriacou Bioessays in press.

2. C. P. Kyriacou L. A. Sawyer A. Piccin M. E. Couchman D. Chalmers Semin. Cell Dev. Biol. 7 803 (1996).

3. RIGUI, a Putative Mammalian Ortholog of the Drosophila period Gene

4. Circadian oscillation of a mammalian homologue of the Drosophila period gene

5. Molecular Transfer of a Species-specific Behavior from Drosophila simulans to Drosophila melanogaster

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