The Role of Somatic Hypermutation in the Generation of Antibody Diversity-Reference-Cited by-同舟云学术

The Role of Somatic Hypermutation in the Generation of Antibody Diversity

Published:1989-06-09 Issue:4909 Volume:244 Page:1152-1157
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

French Deborah L.¹,Laskov Reuven²,Scharff Matthew D.¹

Affiliation:

1. Department of Cell Biology and the Irvington House Institute for Medical Research, Albert Einstein College of Medicine, Bronx, NY 10461.

2. Hubert H. Humphrey Center for Experimental Medicine and Cancer Research, Hebrew University-Hadassah Medical School, Jerusalem, Israel.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference97 articles.

1. ADETUGBO, K, MOLECULAR ANALYSIS OF SPONTANEOUS SOMATIC MUTANTS, NATURE 265: 299 (1977).

2. ALLEN, D, ANTIBODY ENGINEERING FOR THE ANALYSIS OF AFFINITY MATURATION OF AN ANTI-HAPTEN RESPONSE, EMBO JOURNAL 7: 1995 (1988).

3. ALLEN, D, TIMING, GENETIC REQUIREMENTS AND FUNCTIONAL CONSEQUENCES OF SOMATIC HYPERMUTATION DURING B-CELL DEVELOPMENT, IMMUNOLOGICAL REVIEWS 96: 5 (1987).

4. ALT, F.W., JOINING OF IMMUNOGLOBULIN HEAVY-CHAIN GENE SEGMENTS - IMPLICATIONS FROM A CHROMOSOME WITH EVIDENCE OF 3 D-JH FUSIONS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 79: 4118 (1982).

5. Development of the Primary Antibody Repertoire

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