Viral Strategies of Immune Evasion

Author:

Ploegh Hidde L.1

Affiliation:

1. The author is in the Department of Pathology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA.

Abstract

The vertebrate body is an ideal breeding ground for viruses and provides the conditions that promote their growth, survival, and transmission. The immune system evolved and deals with this challenge. Mutually assured destruction is not a viable evolutionary strategy; thus, the study of host-virus interactions provides not only a glimpse of life at immunity's edge, but it has also illuminated essential functions of the immune system, in particular, the area of major histocompatibility complex–restricted antigen presentation.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference48 articles.

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