Comment on “Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome”

Author:

van der Meer Jos W. M.12,Netea Mihai G.12,Galama Jochem M. D.32,van Kuppeveld Frank J. M.32

Affiliation:

1. Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands.

2. Nijmegen Institute for Infection, Inflammation and Immunity, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands.

3. Department of Medical Microbiology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands.

Abstract

Lombardi et al . (Reports, 23 October 2009, p. 585) reported detection of the human gammaretrovirus XMRV in the blood cells of patients with chronic fatigue syndrome (CFS). However, the patient description provided was incomplete. The inclusion of patients from a “CFS outbreak” previously linked with a viral infection, without confirmation in sporadic CFS cases, casts doubt on the role of XMRV in the pathogenesis of CFS.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference17 articles.

1. Chronic fatigue syndrome

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3. J. A. Mikovits presentation at Conference on Cellular and Cytokine Interactions in Health and Disease Lisbon Portugal 17 to 21 October 2009.

4. A cluster of patients with a chronic mononucleosis-like syndrome. Is Epstein-Barr virus the cause?

5. Chronic fatigue syndrome in northern Nevada;Daugherty S. A.;Rev. Infect. Dis.,1991

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