Cancer and Telomeres—An ALTernative to Telomerase-Reference-Cited by-同舟云学术

Cancer and Telomeres—An ALTernative to Telomerase

Published:2012-06-15 Issue:6087 Volume:336 Page:1388-1390
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Shay Jerry W.¹,Reddel Roger R.²,Wright Woodring E.¹

Affiliation:

1. Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA and CEGMR, KAU, Jeddah, Saudi Arabia.

2. Cancer Research Unit, Children's Medical Research Institute, Westmead, NSW 2145 and Sydney Medical School, University of Sydney, NSW 2006, Australia.

Abstract

Finding ways to target the alternative (ALT) telomere lengthening pathway found in some cancer cells could complement telomerase inhibitors currently in clinical trials.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference16 articles.

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2. Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

3. Shay J. W., Bacchetti S., Eur. J. Cancer 33, 787 (1997).

4. Ouellette M. M., Wright W. E., Shay J. W., J. Cell. Mol. Med. 15, 1433 (2011).

5. Bryan T. M., Englezou A., Dalla-Pozza L., Dunham M. A., Reddel R. R., Nat. Med. 3, 1271 (1997).

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