Mitochondrial FtsZ in a Chromophyte Alga

Author:

Beech Peter L.12,Nheu Thao2,Schultz Thomas2,Herbert Shane1,Lithgow Trevor3,Gilson Paul R.42,McFadden Geoffrey I.42

Affiliation:

1. Centre for Cellular and Molecular Biology, School of Biological and Chemical Sciences, Deakin University, 221 Burwood Highway, Melbourne, 3125, Australia.

2. School of Botany,

3. Department of Biochemistry and Molecular Biology, University of Melbourne, 3010, Australia.

4. Plant Cell Biology Research Centre,

Abstract

A homolog of the bacterial cell division gene ftsZ was isolated from the alga Mallomonas splendens. The nuclear-encoded protein (MsFtsZ-mt) was closely related to FtsZs of the α-proteobacteria, possessed a mitochondrial targeting signal, and localized in a pattern consistent with a role in mitochondrial division. Although FtsZs are known to act in the division of chloroplasts, MsFtsZ-mt appears to be a mitochondrial FtsZ and may represent a mitochondrial division protein.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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