Cancer BiomarkersAn Invitation to the Table-Reference-Cited by-同舟云学术

Cancer BiomarkersAn Invitation to the Table

Published:2006-05-26 Issue:5777 Volume:312 Page:1165-1168
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Dalton William S.¹²,Friend Stephen H.¹²

Affiliation:

1. H. Lee Moffitt Cancer Center, University of South Florida, Tampa, FL 33613, USA.

2. Merck Research Laboratories, West Point, PA 19846, USA.

Abstract

The allure of the emerging genomic technologies in cancer is their ability to generate new biomarkers that predict how individual cancer patients will respond to various treatments. However, productive implementation of cancer biomarkers into patient care will require fundamental changes in how we consider approvals for cancer indications and how we track patient responses. Here we briefly describe ongoing efforts to identify and to validate cancer biomarkers, discuss the technological hurdles that lie ahead, and then focus on the more pressing political and cultural issues that, if left unheeded, could derail many of the anticipated benefits of biomarker research.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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