A method for single-neuron chronic recording from the retina in awake mice-Reference-Cited by-同舟云学术

A method for single-neuron chronic recording from the retina in awake mice

Published:2018-06-29 Issue:6396 Volume:360 Page:1447-1451
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Hong Guosong¹^ORCID,Fu Tian-Ming¹,Qiao Mu²^ORCID,Viveros Robert D.³,Yang Xiao¹^ORCID,Zhou Tao¹^ORCID,Lee Jung Min¹⁴^ORCID,Park Hong-Gyu¹⁴^ORCID,Sanes Joshua R.²^ORCID,Lieber Charles M.¹³^ORCID

Affiliation:

1. Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.

2. Center for Brain Science and Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA.

3. John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.

4. Department of Physics, Korea University, Seoul, Republic of Korea.

Abstract

Eye can see neural activity Organisms take up a tremendous amount of information through the visual system, which is then processed by the neural circuitry. Hong et al. developed a mesh electronics implant that is delivered by injection into mice retinas. With these devices, it is possible to obtain recordings from retinal ganglion cells over long time periods in awake, active mice. Both orientation- and direction-selective retinal ganglion cells can be monitored, as can the circadian modulation of retinal ganglion cell activity. Science , this issue p. 1447

Funder

National Institute on Aging

NIH Office of the Director

NIH Blueprint for Neuroscience Research

Air Force Office of Scientific Research

American Heart Association

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference43 articles.

1. The Neuronal Organization of the Retina