Affiliation:
1. Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06510
Abstract
Adenosine 3′,5′-monophosphate at a concentration of 5 × 10
-7
mole per liter causes a 400 percent increase in the rate of phosphorylation of histone catalyzed by a partially purified enzyme preparation from rabbit brain. The data provide the first direct evidence of a biochemical action of adenosine 3′,5′-monophosphate in the brain.
Publisher
American Association for the Advancement of Science (AAAS)
Reference16 articles.
1. BUTCHER, R.W., ADENOSINE 3',5'-PHOSPHATE IN BIOLOGICAL MATERIALS .1. PURIFICATION AND PROPERTIES OF CYCLIC 3',5'-NUCLEOTIDE PHOSPHODIESTERASE AND USE SF THIS ENZYME TO CHARACTERIZE ADENOSINE 3',5'-PHOSPHATE IN HUMAN URINE, JOURNAL OF BIOLOGICAL CHEMISTRY 237: 1244 (1962).
2. DELANGE, R.J., ACTIVATION OF SKELETAL MUSCLE PHOSPHORYLASE KINASE BY ADENOSINE TRIPHOSPHATE AND ADENOSINE 3',5'-MONOPHOSPHATE, JOURNAL OF BIOLOGICAL CHEMISTRY 243: 2200 (1968).
3. DEROBERTIS, E, SUBCELLULAR DISTRIBUTION OF ADENYL CYCLASE AND CYCLIC PHOSPHODIESTERASE IN RAT BRAIN CORTEX, JOURNAL OF BIOLOGICAL CHEMISTRY 242: 3487 (1967).
4. GREENGARD, P, ENZYMATIC ADENYLYLATION OF PYROPHOSPHATE BY 3FT 5FT CYCLIC AMP REVERSAL OF ADENYL CYCLASE REACTION, FEDERATION PROCEEDINGS 28: 467 (1969).
5. KAKIUCHI, S, INFLUENCE OF CHEMICAL AGENTS ON ACCUMULATION OF ADENOSINE 3',5'-PHOSPHATE IN SLICES OF RABBIT CEREBELLUM, MOLECULAR PHARMACOLOGY 4: 367 (1968).
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