The Human Genome Project: Lessons from Large-Scale Biology-Reference-Cited by-同舟云学术

The Human Genome Project: Lessons from Large-Scale Biology

Published:2003-04-11 Issue:5617 Volume:300 Page:286-290
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Collins Francis S.¹,Morgan Michael²,Patrinos Aristides³

Affiliation:

1. National Human Genome Research Institute, National Institutes of Health, Building 31, Room 4B09, 9000 Rockville Pike, Bethesda, MD 20892, USA.

2. The Wellcome Trust, 183 Easton Road, London NW1 2BE, England.

3. U.S. Department of Energy, 1000 Independence Avenue, S.W., Washington, DC 20585, USA.

Abstract

The Human Genome Project has been the first major foray of the biological and medical research communities into “big science.” In this Viewpoint, we present some of our experiences in organizing and managing such a complicated, publicly funded, international effort. We believe that many of the lessons we learned will be applicable to future large-scale projects in biology.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference16 articles.

1. J. D. Watson The New York Times 5 June 1990 p. C1.

2. W. H. Lambright Managing “Big Science”: A Case Study of the Human Genome Project (The Price Waterhouse Coopers Endowment for the Business of Government Arlington VA 2002). Available at www.endowment.pwcglobal.com/pdfs/LambrightReport2.pdf.

3. The Human Genome Project: Past, Present, and Future

4. J. Sulston G. Ferry The Common Thread: A Story of Science Politics Ethics and the Human Genome (Joseph Henry Press Washington DC 2002) pp. 73–76.

5. The Human Genome Project: A Player's Perspective

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