Suppression of Avian Influenza Transmission in Genetically Modified Chickens-Reference-Cited by-同舟云学术

Suppression of Avian Influenza Transmission in Genetically Modified Chickens

Published:2011-01-14 Issue:6014 Volume:331 Page:223-226
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Lyall Jon¹,Irvine Richard M.²,Sherman Adrian³,McKinley Trevelyan J.¹,Núñez Alejandro²,Purdie Auriol³,Outtrim Linzy²,Brown Ian H.²,Rolleston-Smith Genevieve³,Sang Helen³,Tiley Laurence¹

Affiliation:

1. Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK.

2. Veterinary Laboratories Agency, Weybridge, Addlestone, Surrey KT15 3NB, UK.

3. The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh EH25 9PS, UK.

Abstract

Transgenic birds expressing a short hairpin RNA that blocks viral polymerase hinder influenza transmission.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference14 articles.

1. Interspecies Transmission of Influenza Viruses

2. Control and prevention of avian influenza in an evolving scenario

3. Efficacy of Vaccines in Chickens against Highly Pathogenic Hong Kong H5N1 Avian Influenza

4. Developments in transgenic technology: applications for medicine

5. Genetic Strategy to Prevent Influenza Virus Infections in Animals

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