Cortical information flow during flexible sensorimotor decisions

Author:

Siegel Markus12,Buschman Timothy J.23,Miller Earl K.2

Affiliation:

1. Centre for Integrative Neuroscience and MEG Center, University of Tübingen, Tübingen, Germany.

2. Picower Institute for Learning and Memory and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

3. Princeton Neuroscience Institute and Department of Psychology, Princeton University, Princeton, NJ 08544, USA.

Abstract

Signal flow during sensorimotor choices Little is known about the flow of task signals across the brain. Siegel et al. simultaneously recorded from multiple units in the sensory, parietal, prefrontal, and motor cortex while monkeys were cued to perform one among two possible simple tasks. The proportion of neurons coding for stimuli, cues, tasks, and choices, and their response latency, varied across regions. Parietal and prefrontal brain regions encoded task information and choices with the same latency. Interestingly, all brain areas encoded all types of information. However, they differed functionally according to the proportions of neurons and their response latency. Science , this issue p. 1352

Funder

National Institutes of Health

National Institute for Mental Health

Deutsche Forschungsgemeinschaft

MIT Picower Innovation Fund

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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