A Neutralizing Antibody Selected from Plasma Cells That Binds to Group 1 and Group 2 Influenza A Hemagglutinins

Author:

Corti Davide12,Voss Jarrod3,Gamblin Steven J.3,Codoni Giosiana1,Macagno Annalisa1,Jarrossay David1,Vachieri Sebastien G.3,Pinna Debora1,Minola Andrea1,Vanzetta Fabrizia2,Silacci Chiara1,Fernandez-Rodriguez Blanca M.1,Agatic Gloria2,Bianchi Siro2,Giacchetto-Sasselli Isabella1,Calder Lesley3,Sallusto Federica1,Collins Patrick3,Haire Lesley F.3,Temperton Nigel4,Langedijk Johannes P. M.5,Skehel John J.3,Lanzavecchia Antonio16

Affiliation:

1. Institute for Research in Biomedicine, 6500 Bellinzona, Switzerland.

2. Humabs BioMed SA, 6500 Bellinzona, Switzerland.

3. Medical Research Council (MRC) National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.

4. Viral Pseudotype Unit, School of Pharmacy, University of Kent, Kent ME4 4TB, UK.

5. Pepscan Therapeutics BV, Lelystad, 8243 RC, Netherlands.

6. Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, 8032 Zürich, Switzerland.

Abstract

An antibody able to broadly neutralize both group 1 and group 2 influenza A viruses—and its target epitope—are identified.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3