Affiliation:
1. Department of Anatomy, Embryology and Physiology, Academic Medical Center, Amsterdam, Netherlands.
Abstract
Digital reconstruction of human development
The detailed morphology of human development has intrigued scientists and the medical field alike. However, the scarcity of specimens hampers detailed mapping of tissue architecture. Furthermore, inaccuracies in the description of human development have crept into textbooks from observations of animal models that are extrapolated to humans. By mapping normal developmental processes and patterns, such as the growth and relative placement of organs, congenital anomalies can be better understood. de Bakker
et al.
generated interactive three-dimensional digital reconstructions based on the Carnegie collection of histologically sectioned human embryos spanning the first 2 months of gestation. These interactive models will serve as educational and scientific resources for normal and abnormal human development.
Science
, this issue p.
10.1126/science.aag0053
Publisher
American Association for the Advancement of Science (AAAS)
Reference51 articles.
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