Hepatic Microsomal Enzymes in Man and Rat: Induction and Inhibition by Ethanol

Author:

Rubin Emanuel1,Lieber Charles S.2

Affiliation:

1. Department of Pathology, Mount Sinai School of Medicine, City University of New York, New York 10029

2. Section of Liver Disease and Nutrition, Bronx Veterans Administration Hospital, and Department of Medicine, Mount Sinai School of Medicine

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference10 articles.

1. CONNEY, A.H., PHARMACOLOGICAL IMPLICATIONS OF MICROSOMAL ENZYME INDUCTION, PHARMACOLOGICAL REVIEWS 19: 317 (1967).

2. FOUTS, J.R., THE ENZYMATIC REDUCTION OF CHLORAMPHENICOL, PARA-NITROBENZOIC ACID AND OTHER AROMATIC NITRO COMPOUNDS IN MAMMALS, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 119: 197 (1957).

3. IMAI, Y, ACTIVATION AND INHIBITION OF MICROSOMAL HYDROXYLATION BY ETHYL ISOCYANIDE, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 25: 80 (1966).

4. JONES, A.L., INCREASED CHOLESTEROL BIOSYNTHESIS FOLLOWING PHENOBARBITAL INDUCED HYPERTROPHY OF AGRANULAR ENDOPLASMIC RETICULUM IN LIVER, PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 119: 1136 (1965).

5. KUNTZMAN, R, METABOLISM OF DRUGS AND CARCINOGENS BY HUMAN LIVER ENZYMES, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 152: 151 (1966).

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