Cellodextrin Transport in Yeast for Improved Biofuel Production

Author:

Galazka Jonathan M.1,Tian Chaoguang23,Beeson William T.4,Martinez Bruno5,Glass N. Louise2,Cate Jamie H. D.145

Affiliation:

1. Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720, USA.

2. Department of Plant and Microbial Biology, University of California at Berkeley, Berkeley, CA 94720, USA.

3. Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Xiqi Dao 32, Tianjin Airport Economic Area, Tianjin 300308, China.

4. Department of Chemistry, University of California at Berkeley, Berkeley, CA 94720, USA.

5. Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.

Abstract

Improving Yeast for Biofuel Production The biofuels industry uses the yeast Saccharomyces cerevisiae to produce ethanol from sugars derived from cornstarch or sugar cane. Plant cell walls are an attractive sugar source; however, yeast does not grow efficiently on cellulose–derived sugars (cellodextrins). Galazka et al. (p. 84 , published online 9 September) now show that a model cellolytic fungus Neurospora crassa relies on a cellodextrin transport system to facilitate growth on cellulose. Yeast reconstituted with this transport system grew efficiently on cellodextrins, which could potentially improve the efficiency of cellulosic biofuel production.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference21 articles.

1. United States Department of Agriculture (USDA) “The economic feasibility of ethanol production from sugar in the United States” (USDA Washington DC 2006).

2. Genomics of cellulosic biofuels

3. Challenges in Engineering Microbes for Biofuels Production

4. Biomass Recalcitrance: Engineering Plants and Enzymes for Biofuels Production

5. Microbial Cellulose Utilization: Fundamentals and Biotechnology

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