Changes in Auxin Response from Mutations in an AUX/IAA Gene

Author:

Rouse Dean12,Mackay Pamela12,Stirnberg Petra12,Estelle Mark12,Leyser Ottoline12

Affiliation:

1. D. Rouse, P. Mackay, P. Stirnberg, O. Leyser, Department of Biology, University of York, York YO1 5YW, UK.

2. M. Estelle, Department of Biology, Indiana University, Bloomington, IN 47405, USA.

Abstract

Transcription of the AUX/IAA family of genes is rapidly induced by the plant hormone auxin, but evidence that AUX/IAA genes mediate further responses to auxin has been elusive. Changes in diverse auxin responses result from mutations in the Arabidopsis AXR3 gene. AXR3 was shown to be a member of the AUX/IAA family, providing direct evidence that AUX/IAA genes are central in auxin signaling. Molecular characterization of axr3 gain-of-function and loss-of-function mutations established the functional importance of domains conserved among AUX/IAA proteins.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference33 articles.

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3. . A mutant phenotypically indistinguishable from axr3-1 was donated by K. Schneider and K. Roberts. The mutation maps to the AXR3 locus and hence was designated axr3-4.

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5. Ainley W. M., Walker J. C., Nagao R., Key J. L., J. Biol. Chem. 263, 10658 (1988);

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