Recyclable surgical, consumer, and industrial adhesives of poly(α-lipoic acid)

Author:

Pal Subhajit1ORCID,Shin Jisoo1,DeFrates Kelsey1ORCID,Arslan Mustafa12ORCID,Dale Katelyn1,Chen Hannah3,Ramirez Dominic1ORCID,Messersmith Phillip B.134ORCID

Affiliation:

1. Department of Bioengineering, University of California, Berkeley, CA 94720, USA.

2. Department of Chemistry, Faculty of Science and Letters, Kirklareli University, Kirklareli 39100, Türkiye.

3. Department of Materials Science and Engineering, University of California, Berkeley, CA 94720, USA.

4. Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.

Abstract

Polymer adhesives play an important role in many medical, consumer, and industrial products. Polymers of α-lipoic acid (αLA) have the potential to fulfill the need for versatile and environmentally friendly adhesives, but their performance is plagued by spontaneous depolymerization. We report a family of stabilized αLA polymer adhesives that can be tailored for a variety of medical or nonmedical uses and sustainably sourced and recycled in a closed-loop manner. Minor changes in monomer composition afforded a pressure-sensitive adhesive that functions well in dry and wet conditions, as well as a structural adhesive with strength equivalent to that of conventional epoxies. αLA surgical superglue successfully sealed murine amniotic sac ruptures, increasing fetal survival from 0 to 100%.

Publisher

American Association for the Advancement of Science (AAAS)

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