Rational Design of Potent Antagonists to the Human Growth Hormone Receptor
Author:
Affiliation:
1. Department of Protein Engineering, Genentech, Inc., South San Francisco, CA 94080.
2. Osaka Bioscience Institute, 6-2-4 Furuedai, Suita-shi, Osaka 565, Japan.
3. Department of Molecular Biology, Genentech, Inc., South San Francisco, CA 94080.
Publisher
American Association for the Advancement of Science (AAAS)
Subject
Multidisciplinary
Reference23 articles.
1. BARNARD, R, EVIDENCE FROM THE USE OF MONOCLONAL-ANTIBODY PROBES FOR STRUCTURAL HETEROGENEITY OF THE GROWTH-HORMONE RECEPTOR, BIOCHEMICAL JOURNAL 231: 459 (1985).
2. BAS, S.H., PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88: 4498 (1991).
3. BAZAN, J.F., STRUCTURAL DESIGN AND MOLECULAR EVOLUTION OF A CYTOKINE RECEPTOR SUPERFAMILY, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 87: 6934 (1990).
4. CHEN, W.Y., GLYCINE-119 OF BOVINE GROWTH-HORMONE IS CRITICAL FOR GROWTH-PROMOTING ACTIVITY, MOLECULAR ENDOCRINOLOGY 5: 1845 (1991).
5. COSMAN, D, A NEW CYTOKINE RECEPTOR SUPERFAMILY, TRENDS IN BIOCHEMICAL SCIENCES 15: 265 (1990).
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